FBackup

FBackup is a capable file backup tool, free for both personal and commercial use. The interface is simple and straightforward, and there are a number of features you don't always see elsewhere.

Plug-ins allow you to back up individual programs with a click; there's support for include and exclude filters; and you can run "mirror" backups, which just copy everything without zipping it up (which makes restoring files very easy).

Compression isn't so good, though (it's the weak Zip2), and the scheduler is also more basic than you'll see elsewhere. But if your needs are simple (or you're tired of "free for personal use" tools) then FBackup should appeal.